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For example, testosterone undecanoate, anavar and primobolan are just some oral steroids that pose little to no hepatic (liver) strainrisk. In fact, their hepatic inhibition has been documented in some rare cases!A few other things with respect to testosterone are:1. It appears to be safe in healthy individuals for both the testosterone and the testosterone ester. However, due to its liver-related hepatotoxicity, this is not a general recommendation.2. It may cause a higher risk of liver problems (hepatic hyperplasia, cysts, hepatocytes with a fibrotic growth center on their apical membranes) when taken as a single dose.3. When taken as a single dose over a long-term, it may increase serum total cholesterol, triglycerides and plasma HDL and LDL cholesterol by at least as much as it increases testosterone.4. The only known hepatotoxic effect of testosterone is its hepatic effect. However, this hepatotoxicity is not yet well understood and is probably not a systemic risk.5. It is a potent inhibitor of insulin which may increase the risk of diabetes.6. It may increase the risk of liver tumours as well as a reduction of insulin sensitivity and insulin responsiveness in some people.The side effects and interactions with other medicines are listed in the section on interaction of medicines in the prescribing Information for the Patient.Topical testosterone undecanoate / Testolin - Side effectsAccording to the clinical trial data, testosterone undecanoate/Testolin may also cause an improvement of the following diseases:Pregnancy: Lowered testosterone levels in pregnant women may be of concern. This should be taken with caution.Hepatic hyperplasia (cysts, fibrosis): Reduced risk of hepatic fibrosis as well as reduced risk of hepatic cysts or fibrosis with testosterone supplementation.Endometriosis (womb lining, carcinoma): Reduced risk of recurrence of endometriosis.Tumour necrosis factor (TNF): Decreased incidence of tumours in men with androgen deficiency.Inflammation and Inflammasome: Decreased inflammatory markers and reduced incidence of autoimmune (TNF) syndrome (myofascial trigger syndrome) and T cells (Chen et al).Fibrosis: Decreased risk of Fibrotic changes or Fibrosis.Altered sexual function and a lowered libido with low testosterone levels may be of concern. This should be taken with caution to counteractRelated Article: